OSSSC Nursing Disease Guide

Last-hour review

Rapid revision

Compact cross-disease facts for fast recall before the examination.

National Immunisation Schedule: the minimum table

  • Bacillus Calmette–Guérin: Intradermal, left upper arm.
  • Oral Polio Vaccine and rotavirus vaccine: Oral.
  • Fractional Inactivated Polio Vaccine: Intradermal.
  • Pentavalent and Pneumococcal Conjugate Vaccine: Intramuscular.
  • Measles-Rubella: Subcutaneous in the national schedule.
  • Never freeze: Pentavalent, Diphtheria-Pertussis-Tetanus, Tetanus-diphtheria, hepatitis B, Pneumococcal Conjugate Vaccine, and Inactivated Polio Vaccine are freeze-sensitive.
  • Freeze-dried vaccines: Bacillus Calmette–Guérin, Measles-Rubella, and Japanese encephalitis require supplied diluent and timely use after reconstitution according to policy.
  • Mission Indradhanush: Reaches children and pregnant women who are unvaccinated or partially vaccinated; it does not create a different routine schedule.
  • Human Papillomavirus 2026 campaign: Do not insert it into the infant table; remember it separately as the age-14 nationwide campaign.

Age: Birth

Vaccines to remember: Bacillus Calmette–Guérin, birth dose Oral Polio Vaccine, hepatitis B birth dose

Age: 6 weeks

Vaccines to remember: Oral Polio Vaccine 1, pentavalent 1, fractional Inactivated Polio Vaccine 1, rotavirus 1, Pneumococcal Conjugate Vaccine 1

Age: 10 weeks

Vaccines to remember: Oral Polio Vaccine 2, pentavalent 2, rotavirus 2

Age: 14 weeks

Vaccines to remember: Oral Polio Vaccine 3, pentavalent 3, fractional Inactivated Polio Vaccine 2, rotavirus 3, Pneumococcal Conjugate Vaccine 2

Age: 9–12 months

Vaccines to remember: Measles-Rubella 1, Japanese encephalitis 1 in selected endemic districts, Pneumococcal Conjugate Vaccine booster, fractional Inactivated Polio Vaccine 3, first vitamin A dose

Age: 16–24 months

Vaccines to remember: Measles-Rubella 2, Japanese encephalitis 2 in selected endemic districts, Diphtheria-Pertussis-Tetanus booster 1, Oral Polio Vaccine booster, vitamin A follow-up

Age: 5–6 years

Vaccines to remember: Diphtheria-Pertussis-Tetanus booster 2

Age: 10 years

Vaccines to remember: Tetanus-diphtheria vaccine

Age: 16 years

Vaccines to remember: Tetanus-diphtheria vaccine

Age: Pregnancy

Vaccines to remember: Tetanus-diphtheria dose 1, dose 2 after 4 weeks; booster if adequately vaccinated in a recent pregnancy, per history/protocol

Vector and reservoir table

Disease: Malaria

Vector / key reservoir: Female Anopheles

One distinguishing fact: Mainly night biting; parasite is Plasmodium

Disease: Dengue

Vector / key reservoir: Aedes aegypti

One distinguishing fact: Day biting; container breeding

Disease: Chikungunya

Vector / key reservoir: Aedes

One distinguishing fact: Fever with severe persistent joint pain

Disease: Lymphatic filariasis

Vector / key reservoir: Culex quinquefasciatus

One distinguishing fact: Mass Drug Administration + morbidity management

Disease: Japanese encephalitis

Vector / key reservoir: Culex vishnui group; pigs amplify

One distinguishing fact: Humans are dead-end hosts

Disease: Kala-azar

Vector / key reservoir: Female sandfly

One distinguishing fact: Prolonged fever + splenomegaly

Disease: Scrub typhus

Vector / key reservoir: Chigger mite

One distinguishing fact: Eschar; OX-K association

Disease: Leptospirosis

Vector / key reservoir: Animal urine, especially rodents; no arthropod vector

One distinguishing fact: Floodwater exposure + calf tenderness + conjunctival suffusion

Disease: Rabies

Vector / key reservoir: Infected mammals, mainly dogs; no arthropod vector

One distinguishing fact: Immediate wound washing + post-exposure prophylaxis

Screening versus diagnostic confirmation

Condition: Hypertension

Screening / first step: Standardised blood-pressure measurement

Confirmation or next step: Repeat/confirm on another occasion unless urgent

Condition: Diabetes

Screening / first step: Capillary glucose in programme screening

Confirmation or next step: Laboratory plasma glucose, Oral Glucose Tolerance Test, or glycated haemoglobin as appropriate

Condition: Oral cancer

Screening / first step: Visual oral examination

Confirmation or next step: Specialist examination and biopsy

Condition: Breast cancer

Screening / first step: Clinical Breast Examination

Confirmation or next step: Imaging and tissue/cytology diagnosis

Condition: Cervical cancer

Screening / first step: Visual Inspection with Acetic Acid

Confirmation or next step: Colposcopic assessment/biopsy according to protocol

Condition: Tuberculosis

Screening / first step: Symptoms/risk assessment and chest X-ray

Confirmation or next step: Molecular test, microscopy/culture as indicated

Condition: Human Immunodeficiency Virus

Screening / first step: Reactive screening assay

Confirmation or next step: Complete the national serial-testing algorithm

Condition: Hepatitis C

Screening / first step: Anti-hepatitis C virus antibody

Confirmation or next step: Hepatitis C virus ribonucleic-acid test for active infection

Condition: Malaria

Screening / first step: Suspected febrile illness

Confirmation or next step: Rapid Diagnostic Test or microscopy

Condition: Sickle-cell disorder

Screening / first step: Solubility/sickling test where used

Confirmation or next step: High-Performance Liquid Chromatography or haemoglobin electrophoresis

Integrated Disease Surveillance Programme forms

  • S form: Suspected cases, generally reported by health workers.
  • P form: Presumptive/probable cases based on clinical diagnosis, generally reported by clinicians.
  • L form: Laboratory-confirmed cases, reported by laboratories.
  • Reporting week: Monday through Sunday in the traditional weekly system.
  • Integrated Health Information Platform: Moves surveillance toward near-real-time, case-based digital reporting; national rollout began 5 April 2021, and Odisha migrated in 2022.
  • Outbreak logic: An unusual increase above expected occurrence matters; one case may be an outbreak for a disease normally absent from an area.
  • Notification is not the same as diagnosis: A notifiable suspected/confirmed event must be reported through the required channel; reporting should not be delayed for avoidable administrative reasons.

Isolation, disinfection, and transmission shortcuts

  • Airborne: Tuberculosis, measles, varicella—respirator-level protection and appropriate ventilation/airborne precautions.
  • Droplet: Diphtheria, pertussis, meningococcal disease, influenza—surgical-mask/droplet precautions plus standard precautions.
  • Contact/faeco-oral: Acute diarrhoeal illness, rotavirus—hand hygiene, safe excreta disposal, environmental cleaning.
  • Standard precautions: Apply to every patient; treat blood/body fluids as potentially infectious.
  • Sterilisation: Destroys all microbial life including spores.
  • Disinfection: Eliminates many/all pathogenic organisms but may not destroy bacterial spores.
  • Concurrent disinfection: Done during the illness as infectious material is produced.
  • Terminal disinfection: Done after the patient is discharged, transferred, or no longer infectious.
  • Isolation: Separates ill/infected persons; quarantine restricts exposed persons who are not yet ill.

Awareness days worth memorising

Date: 30 January

Day: Anti-Leprosy Day in India

Date: 4 February

Day: World Cancer Day

Date: 24 March

Day: World Tuberculosis Day

Date: 25 April

Day: World Malaria Day

Date: 31 May

Day: World No Tobacco Day

Date: 28 July

Day: World Hepatitis Day

Date: 28 September

Day: World Rabies Day

Date: 10 October

Day: World Mental Health Day

Date: 14 November

Day: World Diabetes Day

Date: 1 December

Day: World AIDS Day

Antimicrobial resistance and One Health

  • Antimicrobial resistance: A microorganism becomes resistant; the patient’s body does not “become resistant.”
  • Antibiotics do not treat viral infections such as uncomplicated dengue, measles, influenza, or the common cold.
  • Antibiotic stewardship: Use an antibiotic only when indicated, choose the narrowest effective agent, use correct dose/route/duration, review culture results, and de-escalate or stop when appropriate.
  • Culture before antibiotics: Obtain appropriate specimens first when this can be done without dangerously delaying urgent treatment.
  • Infection prevention link: Hand hygiene, vaccination, environmental cleaning, device care, and isolation reduce infections and therefore reduce antibiotic use.
  • National Action Plan on Antimicrobial Resistance 2.0: Current national plan covers 2025–2029 and joins surveillance, prevention, rational antimicrobial use, research, governance, and multisectoral action.
  • One Health: Human, animal, plant, and environmental health are interconnected; zoonotic surveillance and antimicrobial resistance cannot be controlled by the health department alone.
  • National One Health Mission: A whole-of-government/whole-of-society platform for pandemic preparedness, integrated surveillance, joint outbreak investigation, and medical countermeasures.

Last-hour revision

  • 2025 target: Tuberculosis elimination target (remember as target).
  • 2027: Malaria zero indigenous cases; lymphatic-filariasis elimination; leprosy district transmission interruption; Human Immunodeficiency Virus epidemic-control push by 1 December.
  • 2030: Malaria-free certification; hepatitis C elimination; dog-mediated rabies elimination.
  • 2047: Sickle-cell anaemia public-health elimination mission.
  • Age 30+: Government screening for hypertension, diabetes, oral cancer, breast cancer, and cervical cancer.
  • Age 14: 2026 nationwide single-dose quadrivalent Human Papillomavirus vaccination campaign for girls.
  • 1-3-7: Malaria notify-investigate-respond.
  • S-P-L: Suspected–Presumptive–Laboratory surveillance forms.
  • 15 minutes: Rabies wound washing.
  • 24 hours: Discard prepared Oral Rehydration Solution.
  • 14416: Tele-MANAS. 1097: Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome helpline. 15400: Rabies helpline.
  • 2025–2029: National Action Plan on Antimicrobial Resistance 2.0. 12 March 2024: National snakebite action plan launch.
  • Usually curable with correct complete treatment: Tuberculosis, malaria, leprosy, hepatitis C, leptospirosis, scrub typhus, typhoid, and kala-azar.
  • Preventable after exposure but not reliably curable after symptoms: Rabies.
  • Controlled, not routinely cured: Human Immunodeficiency Virus infection, chronic hepatitis B, diabetes, hypertension, asthma, and many mental-health conditions.
  • No specific antiviral cure; supportive care is central: Dengue, chikungunya, measles, and Japanese encephalitis.
  • Irreversible damage may remain: Polio paralysis, chronic filarial lymphoedema, chronic obstructive pulmonary disease airflow damage, glaucoma damage, advanced chronic kidney disease, and established stroke deficits.
  • Cancer: “Cure” depends strongly on cancer type and stage; screening aims to find precancer/early cancer when cure is more likely.